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Exosomes

Enhancing Cell to Cell Communication

When stem cells want to “talk” to each other, they secrete tiny vesicles called Exosomes in order to communicate with other stem cells. Exosomes then carry and transfer their payload and instructions to neighboring cells.

What are Exosomes?

Mesenchymal stem cells (MSCs) are one of the most accessible primary cells and can be easily collected from a large variety of tissues. The ease of isolation and specialized biological functions of MSCs have made them a popular choice for cell therapy research. Their ability to differentiate has characterized them as seeds with therapeutic properties to reconstruct, regenerate and repair. MSCs can produce high amounts of Exosomes, therefore, passing along their therapeutic attributes. Because Exosomes reflect properties of their source cells, younger MSCs produce seven times more Exosomes than older, adult MSCs.

How Do Exosomes Work?

Different cell types release Exosomes that haul specific proteins, lipids and growth factor details to targeted cells in the body. Exosomes securely carry this information and are guided, similar to GPS, by exterior molecules that target the recipient cell. Although this information originates from a person’s cell, there is no DNA transferred within the Exosome payload between bodies or cells.

Once united, the targeted cell absorbs the Exosome, along with its cargo instructions, to begin it’s physiological transformation.

Watch an explanation of Exosomes here.

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  • 8+ Years in Regenerative Medicine Therapies
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